GlaxoSmithKline take away precautionary measures to ensure safety and security as inconsistencies in manufacture space investigated.

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Production and also distribution has been stopped on two products, Excedrin Extra Strength and Excedrin Migraine.Roman Tiraspolsky/Alamy
Two over-the-counter drugs that numerous headache and migraine sufferers depend on, Excedrin Extra Strength and Excedrin Migraine, will certainly be difficult to find in the coming days.

According come a statement native GlaxoSmithKline (GSK), the agency that makes the drugs, production and also distribution have been in the interim halted because of “inconsistencies in just how we transfer and weigh ingredients.”

These inconsistencies were uncovered throughout routine high quality control and assurance measures, according to a statement the company made to CNN. The products include Excedrin Extra stamin Caplets and also Geltabs and Excedrin Migraine Caplets and Geltabs.

GSK has actually voluntarily bring away the measures to suspend production and distribution as a precaution. Based upon the available data, they execute not think the commodities pose a security risk to consumers, according to a firm spokesperson in an email to daily Health.

Still, that’s little consolation to civilization who have come to rely on these assets to relieve pain.

“Millions the migraine sufferers use Excedrin, i m sorry is a mix of commonly accessible acetaminophen, aspirin, and the stimulant caffeine, which so many people consume in your coffee every day and also in chocolate,” claims Nauman Tariq, MBBS, combine professor and also director the Johns Hopkins Headache center in Baltimore. “Halting that is production, although temporarily, will rise the anxiety and frustration in human being with migraines.”

Patient support Paula K. Dumas, founder, CEO, and also managing editor the MigraineAgain.com, agrees.

"Many civilization with migraine think about Excedrin Migraine to it is in a 'first-line' treatment. They'll take it it an initial and hope it knocks the end the pain prior to using a much more sedating medication," states Dumas. "Running out will certainly only an increase anxiety levels, which can make migraine assaults even worse."


The company views this halt together a “short-term issue,” and also production is supposed to begin again shortly. However there is no identify date regarding when that will certainly happen, follow to the GSK spokesperson.

Excedrin Extra stamin is used for momentary pain relief as result of headaches, arthritis, and muscle aches; and Excedrin Migraine insurance claims to help relieve pains in as tiny as 30 minutes.

Other Excedrin products are still available. These incorporate Excedrin anxiety Headache, i beg your pardon does no contain aspirin, and Excedrin PM, which also contains a sleep aid.

For many migraine and also headache sufferers, Excedrin is your go-to medication. “If ns was to buy a various brand, it doesn’t even touch it. Ns haven’t watched it empty prefer this . It’s kind of scary,” Excedrin-user Ashleigh Eldred called ABC-affiliate WSYR. “If I have actually a migraine attack, I’m not sure, if i was to not have any kind of on me, what I would certainly do.”

Eldred is no alone. “Excedrin is a very effective drug that world really like,” states Natalia Murinova, MD, neurologist through UW medication in Seattle. “It’s good if it’s offered sparingly, which method not an ext than four to 6 days every month. If someone has actually headaches one or 2 days per week, Excedrin is safe and effective.”

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Dr. Tariq points the end that consumers have actually options. “Migraine patients that respond fine to Excedrin can conveniently make a combination of separately available aspirin close come 250 mg strength, paracetamol
, and add a little cup the coffee, which need to contain close come 65 mg the caffeine,” he says.

Excedrin Overuse: Too much of a an excellent Thing?

Excedrin is one of the peak drugs world use on your own, yet it have the right to lead to trouble v overuse, states Dr. Murinova. “This is a drug that, if civilization are taking it 10 work a month or more, lock can get into a condition called medication overuse headache,” she says. “If a person is treating 3 or more headaches a week with Excedrin and also have stress, they could an extremely easily be causing themselves to have an ext headaches.”

In enhancement to more headaches, long-term use of Excedrin or a “replacement combination” ~ above a regular basis deserve to also an outcome in damage to kidneys, liver, and stomach, according to Tariq. Patients that take Excedrin or integrate drugs together a replacement for Excedrin have to not usage them frequently, the adds.

Migraines: A Disabling Illness

The world Health organization (WHO) named migraine as one of the 10 most disabling illnesses. Along with the ache of a migraine, countless patients live in are afraid of the next attack, recognized as cephalalgiaphobia.

“Typical ideal practice convention among headache professionals is to prescribe a ‘backup rescue or abortive drug’ to patients,” states Tariq. “In case the first-line drug fails to aid or if it’s no available, patients can use a second-line drug.”

There room different types of drugs available to aid treat migraines. Some examples include:

Triptans, which work by constricting certain blood ship that aid block pain pathways in the brain

Migraine sufferers who require an alternative or additional treatment should talk to their doctor, neurologist, or a headache specialist around these medicine options, claims Tariq.

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Although it might be daunting for patients to be there is no Excedrin, it might be a great time come step earlier and look in ~ the root reasons of their migraines, particularly if they space having an ext than one a week, states Murinova.

“For the majority of people, the headache is primary, meaning it’s not a brain tumor. It’s their brain giving them the alarm because they’re stressed, sleep deprived, not obtaining adequate nutrition, or a combination of those factors and also more,” she says. “This could be an chance to discover ways come take great care the yourself and take a look in ~ other alternatives to aid with headaches.”


"This short-term recall might leave civilization digging v backpacks and also medicine chests to count just how plenty of pills they have actually left," states Dumas. "Maybe that'll make civilization re-evaluate exactly how they're treating assaults in the very first place."